Preemptive analgesia of dexamethasone as compared to ketorolac tromethamine in simple tooth extractions

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Preemptive analgesia of dexamethasone as compared to ketorolac tromethamine in simple tooth extractions*

BACKGROUND AND OBJECTIVES: Understanding that pain is the most important postoperative problem, in face to the need of establishing a therapeutic protocol to control post-tooth extraction pain and due to few studies comparing these drugs is that our study is justified. This study aimed at evaluating and at comparing the preemptive analgesic effect of two drugs, both administered in bolus. METHO...

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Ocular pharmacokinetics of 0.45% ketorolac tromethamine

PURPOSE A new carboxymethylcellulose (CMC)-containing ophthalmic formulation of 0.45% ketorolac, pH 6.8 (Acuvail(®)) was recently developed for treatment of inflammation and pain after cataract surgery. This study compared pharmacokinetics of the new formulation with that of a prior formulation, 0.4% ketorolac, pH 7.4 (Acular LS(®)). METHODS Ketorolac formulations were administered bilaterall...

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Ketorolac tromethamine: A nonsteroidal anti-inflammatory analgesic

This case report describes a general anesthetic where ketorolac tromethamine was used instead of a narcotic. The patient was a 37-year-old male, ASA II category, who underwent general anesthesia for a cholecystectomy. The drug is discussed in terms of preoperative, intraoperative, and immediate postoperative effects. During the preoperative phase, no effect was demonstrated. Intraoperatively, t...

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Analgesia Preemptiva * Preemptive Analgesia

Justificativa e Objetivos O controle da dor pós-operatória tem sido muito investigado nas últimas décadas, quando se verificou que a analgesia pós-operatória era inadequada. O termo “preemptiva” implica em uma forma de analgesia que, iniciada antes do estímulo doloroso ser gerado, previne ou diminui a dor subseqüente. Este estudo tem como objetivo uma atualização sobre analgesia preemptiva poss...

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In-vitro Release Characterization of Ketorolac Tromethamine Loaded Matrix Tablets

The present investigation highlighted the formulation and release characterization of Ketorolac Tromethamine loaded matrix tablet. Various formulations of tablets were prepared by direct compression method along with Kollidon SR and Hydroxy Propyl Methyl Cellulose (HPMC) as release retardant polymers. Each of the formulated tablets contains 50mg Ketorolac Tromethamine. The evaluation involved p...

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ژورنال

عنوان ژورنال: Revista Dor

سال: 2014

ISSN: 1806-0013

DOI: 10.5935/1806-0013.20140034